In Q4 2021 EARL initiated Brain PET/CT accreditation. It is based on a pilot study published by Verwer et. al.¹, and later further refined by Shekari et. al.²

In addition to already active and in good standing either ¹⁸F  standards 1 or 2 accreditation, for the Brain PET/CT accreditation Hoffman 3D Brain phantom images are required to be submitted once per year. This phantom simulates brain uptake of radiopharmaceuticals with a grey matter to white matter ratio (GMWMr) of 4.

The recent methodology to compare and evaluate brain PET image quality from the Hoffman brain phantom was developed and published.² It aims at deriving the effective spatial image resolution from the phantom scans. The proposed method is independent from the accuracy of phantom filling and/or stock solution preparation, and is therefore an attractive approach to assess and harmonize image quality in a multi-center setting. The limits of acceptability for the Brain PET/CT  accreditation are set at 5 to 6 mm FWHM for the observed effective resolution.